In line with our findings of increased CD11b on intestinal neutrophils isolated from female mice exposed to MRSA, studies examining MRSA skin and soft tissue infections found that BM neutrophils from female mice have an enhanced ability to kill MRSA ex vivo compared to those from male mice, which was linked to increases in surface CD11b and antimicrobial production (Castleman et al., 2018; Pokhrel et al., 2020). The gene discussed is ITGAM; the disease is infection.