Our study demonstrated that urine biomarkers, including [TIMP-2]•[IGFBP7], TIMP-2, IGFBP7, NGAL, and L-FABP, provided good predictive performance for any stage of CSA–AKI, with [TIMP-2]•[IGFBP7] showing the best performance. This evidence concerns the gene TIMP2 and acute kidney injury.