AIM2 and cancer: Li et al reported that mitochondrial fission enhances the ADCP effect of macrophages, thereby playing an important role in the phagocytosis of cancer cells.[20] During ADCP, the cell membrane of macrophages is in an unstable state, and the DNA sensor AIM2 can capture mitochondrial DNA from cancer cells through gaps in the membranes of macrophages.[8] In addition, we screened 8 genes that were significantly associated with prognosis using Cox LASSO regression.