Among these, ARID2 and CAPRIN1 are involved in transcriptional regulation,[21,22] AK2 and CAB39 primarily participate in cellular metabolism,[23,24] and AXL, BCL6, and C5AR1 mainly function in immune responses.[25–27] The experimental analysis demonstrated that high expression of C5AR1 in tumors compared to adjacent-normal tissues in STAD. This evidence concerns the gene CAPRIN1 and gastric adenocarcinoma.