Proliferation of basal cells can be donor dependent [25] but wound repair in scratch assay was shown to be slower in CF (CuFi-1) as opposed to non-CF (Nuli-1) cell lines, in primary bronchial epithelial cells from pwCF compared to non-CF (all homozygous for CFTR F508del) and to be associated with a migratory defect that was CFTR dependent [39]. This evidence concerns the gene CFTR and cystic fibrosis.