Conversely, similar pathways were upregulated in AL ovaries, including genes like claudin 7 (cldn7b), involved in solute transfer across cell monolayers and possibly contributing to cancer cell survival, growth, and invasion (Dahiya et al. 2011), and Rhophilin Rho GTPase binding protein 2 (rhpn2), a scaffold protein that participates in protein complex assembly, intracellular signalling, and endosome targeting (Steuve et al. 2006). The gene discussed is CLDN7; the disease is cancer.