The ability of OGM to detect repeat expansions has been demonstrated in over a dozen conditions caused by pathogenic repeat expansions, including neurodegenerative disorders such as Friedreich ataxia (FXN), spinocerebellar ataxia type 10 (ATXN10), spinocerebellar ataxia type 8 (ATNX8), Huntington disease (HTT), and CANVAS (RFC1) [24, 25, 26]. This evidence concerns the gene RFC1 and juvenile Huntington disease.