LDLR and familial hyperaldosteronism: The WMSTM is derived from the once widely used Rapacz-Familial Hypercholesteremia (FH) mini swine, also developed at the university, which carried a clinically relevant mutation in the low-density lipoprotein receptor (LDL-R) associated with high circulating blood cholesterol (Rapacz et al. 1994; Hasler-Rapacz et al. 1998).