The logistic binary regression analysis of the univariate model based on significantly different variables found that age (OR 1.053, 95% CI [1.005–1.104], P = 0.031), BMI (OR 0.854, 95% CI [0.746–0.977], P = 0.022), office DBP (OR 0.961, 95% CI [0.931–0.993], P = 0.016), no hypertension (OR 2.267, 95% CI [1.111–4.627], P = 0.024) and sα1-RAs types were predictive for nocturnal hypotension. The gene discussed is STAG1; the disease is hypertensive disorder.