However, after multivariate adjustment incorporating sα1-RAs types as an additional adjustment factor, only age (OR1.064, 95% CI [1.012–1.118], P = 0.015) and no hypertension (OR 2.548, 95% CI [1.211–5.359], P = 0.014) remained significant associations with nocturnal hypotension. The gene discussed is STAG1; the disease is Hypertension.