Plasma creatinine and general clinical data were collected upon admission.<h4>Results</h4>The level of tumor biomarkers, including carcinoembryonic antigen (CEA), CA125, CA15-3, CA19-9, NSE, proGRP, and HE4, were elevated in patients with CKD (<i>p</i> < 0.05). Here, ENO2 is linked to chronic kidney disease.