Later studies compared ABC and GCB subtypes to show GCB type preferentially mutated in EZH2, SGK1, GNA13, SOCS1, STAT6, and TNFRSF14, and ABC type biased toward mutations ETV6, MYD88, PIM1, and TBL1XR1 (147). This evidence concerns the gene EZH2 and aneurysmal bone cyst.