Neutrophil recruitment is mainly mediated by chemokines with glutamate-leucine-arginine motifs (ELR+ chemokines), mainly melanoma growth-stimulating activity (CXCL1, CXCL2), epithelial neutrophil activating protein (CXCL5), interleukin-8 (CXCL8) [74,76]. Here, CXCL5 is linked to melanoma.