Supplementary Table S1 lists an illustrative set of inherited genetic disorders with reported founder effects. Some genetic disorders show evidence of multiple founder events, each with its own unique haplotype. Examples of founder events include the Huntington’s disease repeat expansion (OMIM: 143100), which displays multiple founder events [7, 14–16], the CFTR p.F508del Cystic fibrosis variant (OMIM: 219700) [17], and the GOSR2 p.G144W progressive myoclonus epilepsy-causing variant (OMIM: 604027) [18]. Here, CFTR is linked to hereditary disease.