Among them, seven cancer genes (ERBB2, ERBB3, PPARG, MYC, CCND1, CCNE1, MDM2) were detected to be amplified in both ctDNA and tumor tissues, indicating the reliability of ctDNA in reflecting the genomic features of tumors (Vandekerkhove et al., 2021). The gene discussed is PPARG; the disease is neoplasm.