DUXAP8 and hepatocellular carcinoma: In addition, lncRNAs can also affect the stability of ferroptosis-related proteins by modulating protein post-translational modifications (e.g., ubiquitination, palmitoylation) (3), e.g., DUXAP8 promotes resistance to sorafenib in hepatocellular carcinoma by enhancing the palmitoylation modification of SLC7A11 and reducing its lysosomal degradation (17).