STAT3 and T-cell large granular lymphocyte leukemia: In turn, T-LGLL cases presented decreased Tregs (p=0.014), particularly within the STAT3 wild-type (p=0.038) and CR- (p=0.036) TαβCD8+ subset of T-LGLL, together with abnormally low Th2 (p=0.037) and Th1 cell numbers, TαβCD4+ LGLL cases (p=0.036) (Figure 5, Supplementary Tables 10, 11, Supplementary Figure 5).