CD4 and neoplasm: In a specific dataset (GSE103322) containing 5,902 single cells derived from 18 patients with HINSCs, SUSD3 expression was found to be particularly evident in CD4+ T conventional cells (Tconv), cytotoxic T lymphocytes, and CD8+ T-exhausted (Tex) cells within the HINSC tumor microenvironment (Figure 3B).