mir-128 can inhibit the proliferation of glioma cells by negatively regulating one of its targets, E2F3a, which is highly expressed in glioma and important for cell cycle progression.54miR-128 up-regulation inhibits DCX and Reelin expression and reduces neuroblastoma cell invasiveness and cell motility in cell lines.55 The gene discussed is RELN; the disease is neuroblastoma.