miR-15a is a target of PPAR- transrepression directly regulates BCL-2 and contributes to PPAR-mediated vascular protection against ischemia-like insults.67miR‐15a regulates oxygen-glucose deprivation/reperfusion (OGD/R)‐induced neuronal injury by targeting BDNF.68 This evidence concerns the gene BDNF and ischemia.