CP and breast carcinoma: However, the role of autophagy in breast cancer is still controversial, with its implications varying depending on the context.27 The aim of this study is to evaluate the combined effects of ATO, CP, and CY on the expression of autophagy-related genes such as LC3 and Beclin 1, as well as their impact on apoptosis in two TNBC cell lines: BT-20 and MDA-MB-231.