It has been reported that in HCC, long noncoding RNA lncFAL can competitively bind to FSP 1, prevent FSP 1 from being degraded by TRIM 69 mediated ubiquitination, and reduce ferroptosis sensitivity; It was also demonstrated that HDLBP combined with lncFAL can stabilize its expression (66). This evidence concerns the gene HDLBP and hepatocellular carcinoma.