GNRH1 and Dravet syndrome: Given our promising results on the effects of gonadotropin-releasing hormone (GnRH) pulsatile therapy on cognition in DS,56 we used relaxometry-based multi-parameter mappings alongside DWI-derived tensor and neurite orientation density and dispersion imaging indices to gain detailed insights into the tissue microstructural underpinnings of morphometry differences between DS and healthy controls across brain’s GM and WM.