CNN1 and Dysmenorrhea: Fibrosis is a major contributor to the resistance to hormonal treatment in adenomyosis,[90] and it is intimately linked to adenomyosis‐induced dysmenorrhea.[91] Myofibroblasts are the main effector cells of fibrosis,[72, 92] resulting from FMT that is triggered by profibrotic mediators.[71, 74] We found that CNN1+ stromal fibroblasts played an important role in fibrogenesis of adenomyosis.