also found higher ESR1 levels in endometrium‐myometrium junction SMCs in the adenomyosis group, which mediated estrogen‐induced aberrant myometrial peristalsis.[81] Adenomyosis is an estrogen‐dependent disease, and estrogen is involved in a variety of biological processes related to adenomyosis pathogenesis.[6, 82] Previous studies have shown the significance of ERα in adenomyosis pathogenesis. The gene discussed is ESR1; the disease is adenomyosis.