To further investigate the correlation between the SFRP5+ epithelial ecotypes and adenomyosis, we employed MuSiC2[31] to estimate SFRP5+ epithelial ecotype proportions in bulk RNA‐seq data of adenomyosis epithelial organoids[20] and found a higher proportion of SFRP5+ epithelial ecotypes within AM group (Figure 2D). This evidence concerns the gene SFRP5 and adenomyosis.