CCS and Alzheimer disease: Although platelet SOD1 levels were increased significantly in AD and MCI patients (FCAD/Co = 1.08; p = 0.036 and FCMCI/Co = 1.09; p = 0.003; Figure 5A), the platelets of patients with AD and MCI had significantly lower CCS levels compared to the cognitively healthy control group (FCAD/Co = 0.92; p = 0.011 and FCMCI/Co = 0.91; p = 0.034; Figure 5B).