ALPL and hypophosphatasia: Literature was searched by keywords of "Hypophosphatasia", "HPP", "ALPL", "TNSALP", "ALP" combined with "Asfotase alfa", "AA", "enzyme replacement therapy", and "ERT".<h4>Results</h4>After unsuccessful 6-month teriparatide treatment for femoral fracture, AA treatment was initiated, at a dose of 2 mg/kg, 3 times a week.