In model 2, adjusted HRs (95% CIs) for 96–100% versus 0–33% YKL-40 percentile category were 2.4 (1.6–3.7) for obesity-related cancers, 2.6 (1.7–4.1) for gastrointestinal cancers, 44.2 (12.8–153.4) for liver cancer, 1.8 (0.4–8.2) for pancreatic cancer, 0.6 (0.2–1.5) for colorectal cancer, 4.2 (1.3–14.1) for bladder cancer, and 1.5 (0.5–4.4) for lung cancer (Figs. 1–2, Supplemental Table 2). The gene discussed is CHI3L1; the disease is familial pancreatic carcinoma.