However, for liver cancer specifically, we find supportive evidence from similar risk estimates observed for alcoholic liver cirrhosis within the previous Danish population cohorts: the HRs for the highest compared to the lowest YKL-40 category were strikingly similar, at 44 in our liver cancer study and 41 in a previous alcoholic liver cirrhosis study [23]. The gene discussed is CHI3L1; the disease is alcoholic liver cirrhosis.