CBS and Dravet syndrome: Markers of H2S production (e.g. thiosulfate) or CBS activity (e.g. homocysteine, cystathionine, lanthionine or others) [11,12,285], along with physiological parameters such as EEG spectral analyses—which are often altered in DS [[286], [287], [288], [289], [290]] and have been shown to normalize with CBS inhibition in preclinical studies [24] — could be incorporated into future clinical trials.