This excessive inflammatory response, commonly referred to as Cytokine Storm Syndrome (CSS) or CRS, manifests as high fever, elevated CRP and ferritin levels, and cytopenias17,18 that can lead to lung damage, ARDS, Multiple Organ Dysfunction Syndrome (MODS), sepsis, and ultimately death.19, 20, 21. The gene discussed is CRP; the disease is Sepsis.