PTCH1 and basal cell carcinoma: Interestingly, none of the described subsequent malignancies in our cohort were ones commonly associated with SUFU or PTCH1 germline alterations.24 If not undertaken at initial diagnosis, a genetic referral at the time of relapse is critical to integrate the risk of basal cell carcinoma or meningioma associated with Gorlin syndrome and radiation exposure.26–28