KLK3 and posterior cortical atrophy: Similar results have been confirmed in other cohorts and been reflected in EAU guidelines, containing a recommendation that serial MRI may be adopted to avoid standard biopsy in men with very low risk of upgrading (low-risk PCa, stable MRI prostate cancer radiological estimation of change in sequential examination (PRECISE) score of 1–3, and a stable and low PSA density of < 0.15 ng/mL/cm3) [45, 46].