In the vehicle-treated mice, we observed significantly more tumor-infiltrated lymph node metastases (Fig. 4D and 2.4 vs 0.8, p = 0.01), more numeric circulating tumor cells (Fig. 4E and 572 vs 172, p = 0.04), and more lung metastases (Fig. 4F and 16 vs 3, p = 0.05) compared to MK2 inhibitor-treated animals. This evidence concerns the gene MAPKAPK2 and neoplasm.