MAPKAPK2 and neoplasm: We saw that control tumor spheroids showed extensive invasion into the microenvironment while loss of MK2 reduced the ability of these cells to spread (Fig. 1E and F) resulting in significantly lower invasion (Fig. 1G; Tu167 = 167 % ± 11.7 % (scr) v 38.2 % ± 6.1 % (shRNA); Cal27 = 25 % ± 1.4 % (scr) v 13 % ± 1.1 % (shRNA)).