MAPKAPK2 and neoplasm: We also observed a significant reduction in overall mean lymph node (2.3 vs 0.7, p = 0.0063) and lung (72.6 vs 1.1, p = 0.0026) metastases in the MK2 knockout tumor implanted mice compared to mice with Ly2 parental WT tumors (Fig. 3D and E).