According to the IHC analysis for Ki‐67 and caspase 3, the PBS group displayed high cell proliferation, while tumor tissues treated with SiO2/Ica‐PDA, SiO2/Ica‐PDA+NIR, and SiO2/Ica‐PDA‐FA showed a gradual decrease in tumor cell proliferation and an increase in apoptotic cells. This evidence concerns the gene MKI67 and neoplasm.