Subsequently, we performed IHC staining to evaluate the expression of P62 and LC3, terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) phosphate buffered saline staining to detect apoptosis, the cell proliferation marker Ki‐67, and the levels of TXNDC9 and HSP90 in mouse tumor tissues. The gene discussed is HSP90AA1; the disease is neoplasm.