Dendritic cells (DCs), as professional antigen‐presenting cells, consist of diverse subsets and play a critical role in immune responses by continuously processing and presenting antigens—a function that is significantly enhanced upon activation.[9] Previous studies have shown that depletion of CD11c+ DCs significantly attenuates AAA expansion in murine models.[10] Nevertheless, the precise roles and mechanisms of DCs in AAA pathogenesis remain insufficiently explored. This evidence concerns the gene ITGAX and triple-A syndrome.