PTGS2 and benign prostatic hyperplasia: However, the a (C) allele of SNP -765 G>C of the PTGS2 gene is significantly more common in the BPH group (OR = 2.30, p-value = 0.01), and notably more common in the combined affected group (OR = 1.59, p-value = 0.07) compared to the control group (Table 2).