One study explored the clinical significance of individual genes in gliomas and developed a prognostic model through an online database.[8] This paper presents our comprehensive analysis of the relationship between SCAMP5 and glioma, assessing SCAMP5 expression in glioma through Chinese Glioma Genome Atlas (CGGA), gene expression profile interactive analysis (GEPIA), and database for annotation, visualization, and integrated discovery (DAVID) data. The gene discussed is SCAMP5; the disease is central nervous system cancer.