Furthermore, there were 62 patients with a CPS A and 28 with a CPS B or C. Looking closer, 24 patients were classified with a CPS A and 6 with a CPS B/C in advanced HCC group; 25 patients were classified with a CPS A and 5 with a CPS B/C in early HCC group; 13 patients were classified with a CPS A and 17 with a CPS B/C in LC without HCC group. The gene discussed is CAD; the disease is laryngotracheoesophageal cleft.