The association between the IL-6 -634C/G, IL-6 -174G/C, and IL-17A -832A/G gene polymorphisms and pneumoconiosis was examined in 5 studies involving 504 patients and 512 controls, 5 studies involving 660 patients and 848 controls, and 5 studies involving 1,179 patients and 1,235 controls. Here, IL17A is linked to pneumoconiosis.