The findings from this study suggest that changes in serum biomarkers, including platelet-derived growth factor-BB, fibrinogen activator inhibitor-1, CCL18, and YKL-40 in patients with idiopathic pulmonary fibrosis (IPF), are associated with the downregulation of Gal-3 (31). Here, LGALS3 is linked to idiopathic pulmonary fibrosis.