For overlapping genes between Anxiety and HNC (Figure 4b), functional enrichment analysis identified terms such as “inflammatory response” (GO:0006954, p = 7.85e-08), involving genes like IL22, IL6, and CXCR4, and the “Toll-like receptor signaling pathway” (hsa04620, p = 1.96e-06) with contributions from IL6 and TLR9. The gene discussed is IL22; the disease is Anxiety.