Lovo-derived EVs triggered a robust increase in the phosphorylation levels of mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK) (p-MEK) and ERK (p-ERK) in a dose-dependent manner, leading to a significant increase in tumor sizes in a xenograft tumor model.7 The gene discussed is MAP2K7; the disease is neoplasm.