Systematic evaluation of PSMD1-14 expression revealed significant upregulation (p<0.05) of PSMD1, PSMD2, PSMD3, PSMD4, PSMD7-PSMD14 transcripts in pancreatic tumor tissues compared with adjacent normal controls, with the notable exception of PSMD6 which demonstrated reduced mRNA expression (Figure 1A). The gene discussed is PSMD14; the disease is pancreatic neoplasm.