PSMD14 and familial pancreatic carcinoma: In addition, this study utilized the PSMD11- and PSMD14-knockdown pancreatic cancer cell lines PANC-1, MIA PaCa-2 and BxPC-3 for functional phenotyping and verified the cancer-promoting functions of PSMD11 and PSMD14 at the in vitro level, which may play key roles in pancreatic carcinogenesis and may be potential targets for pancreatic cancer treatment.