O6-methylguanine DNA-methyltransferase (MGMT) methylation presents with a more favorable prognosis, with a 23 month mOS and a 49% 2-year survival rate, relative to a 13 month mOS and 12% 2-year survival rate for MGMT-promoter unmethylated GBM (4). Here, MGMT is linked to glioblastoma.