IGHE and systemic lupus erythematosus: Therefore, reactivity and frequency of IgE type antibodies against dsDNA, SSA/Ro52, SSA/Ro60, and SSB/La were analysed concerning clinical manifestations including SLEDAI, number of organ manifestations, cutaneous, renal, pulmonary, cardiac, musculoskeletal, gastrointestinal, and haematological manifestation in 90 patients with SLE (Figure 4, Supplementary Table S3).