FTO and rheumatoid arthritis: A series of experimental methods [such as methylated RNA immunoprecipitation-quantitative polymerase chain reaction (MeRIP-qPCR), RNA pull-down, and methylation site mutation] were employed in this study to elucidate the mechanism by which FTO regulated the m6A modification of ENST00000619282 to mediate RA cell apoptosis escape and the interventional role of XFC from the perspective of epigenetic modification, providing new targets and scientific evidence for XFC treatment of RA.