CXCL9 and encephalitis: In a recent study in which a large panel of cytokines and chemokines were assessed in sera of patients receiving ICIs, a significant upregulation of CXCL9, 10, 11 and 13 was closely related to the occurrence of immune-mediated toxicities including pneumonitis, endocrinopathies, dermatitis, arthritis and encephalitis (10).