ADRB2 and heart failure: Future studies of human cardiomyocyte cell lines and human engineered heart tissues using IPSCs will improve our understanding of CM/βAR AAbs in myocarditis and heart failure and test the hypothesis that they may lead to fibrosis in IPSCs or engineered heart tissues containing both fibroblasts and cardiomyocyte IPSCs representing truer models of human disease (128).