For example, reducing ITGA3 expression markedly inhibits the migration and invasion of head and neck squamous cell carcinoma (HNSCC) cells [7], the miR-199 family restrains the migration and invasion of bladder cancer cells by targeting ITGA3 [8], and miR-101 curbs the metastasis and angiogenesis of nasopharyngeal carcinoma (NPC) by targeting ITGA3 [9]. This evidence concerns the gene ITGA3 and urinary bladder cancer.