Instead, Annexin V positivity, caspase‐3 activation, PARP‐1 degradation, and Bcl‐xL protein impairment, indicative of mitochondrial‐dependent apoptotic cell death, were evidenced in AR 292 and AR 357 treated DU‐145 PCa cells. The gene discussed is BCL2L1; the disease is posterior cortical atrophy.