In acute myeloid leukemia (AML), PRMT5 silences miR‐29b expression by H4R3me2, which leads to upregulation of transcription factor “Specificity protein 1” (SP1) and activation of the “Fms‐like tyrosine kinase 3” (FLT3).92 The gene discussed is SP1; the disease is acute myeloid leukemia.