Moreover, plasma p-tau has strong value in differential diagnosis, with high accuracy for discriminating patients with AD from those with frontotemporal dementia (FTD) [7, 8], progressive supranuclear palsy (PSP) [9, 10] and dementia with Lewy bodies (DLB) [11, 12]. The gene discussed is MAPT; the disease is supranuclear palsy, progressive, 1.