IL17A and infection: However, while Nrf2 levels may vary in response to certain stimuli or inflammatory responses, this phenomenon does not always suffice to suppress inflammation, such as in the H2O2-induced astrocyte injury [13], IL-17A-induced inflammatory response of synoviocytes [20], LPS-stimulated macrophage-mediated inflammation [33], and infections caused by Trypanosoma cruzi [15, 34], malaria [34–36], and Leishmania [16, 34].