TNF and polycystic ovary syndrome: They found that women with PCOS exhibited lower levels of C-reactive protein (CRP), interleukin 18 (IL-18), tumor necrosis factor (TNF-α), interleukin 6 (IL-6), and other markers such as white blood cell (WBC) count, MCP-1, and macrophage inflammatory protein-1α (MIP-1α).